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Effect of vitamin C on cholesterol levels and lipoprotein in the rat blood and some other organs | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 15, Issue 2, 2010, Pages 239-245 | ||
| Author | ||
| Abdul kareem A. Alguary | ||
| Abstract | ||
| This study was carried out by using male albino rats , the animals were divided into five groups ,different levels of vitamin C were added to four groups, while the first group with out any additional ratio (control diet ),the levels of vitamin C were (100,250,500,1000) mg kg diet respectively, after feeding of the various vitamin C levels for four weeks the animal were killed . No significant differences in final body weight between the control group and (100,250) mg group while the increase were significant (P≤0.01) among the control group and the others ,there were significant differences (P≤0.01) in the rate of body weight gain among control group and the others, the results show no significant difference in feed intake and feed conversion between the control group and (100) mg group , while the increase were significant(P≤0.01) in others. No significant differences (P≤0.01) in serum cholesterol between control group and (100)mg group, while the decrease was significant among control group and the others, there were significant decrease (P≤0.01) in low density lipoprotein +very low density lipoprotein (LDL+ vLDL) among control group and (100,250,500,1000) mgkg diet groups, but not in high density lipoprotein cholesterol (HDL). The study pointed out presence significant increase(P≤0.01) in liver weight and lipids among control group and other groups, and significant decrease (P≤0.01) in liver cholesterol among control group and the others. There were significant increase (P≤0.01) in heart weight among control group and other groups, there were no significant difference in heart lipids between control group and (250) mg group, while the increase were significant(P≤0.01) with others, there were significant decrease (P≤0.01) in heart cholesterol among control group and others . | ||
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