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Effect Of Toxin Fractions Isolated From Protoscoleces And Hydatid Cyst Fluid Of Sheep Origin On Phagocytosis In Mice | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 15, Issue 2, 2010, Pages 1-4 | ||
| Author | ||
| Nabeel E. Salih | ||
| Abstract | ||
| Effect of toxin fractions of protoscoleces (P) and hydatid cyst fluid (HCF), isolated from hydatid cysts of sheep origin on phagocytosis was investigated. Mice of the species Mus musculus were injected with these TFs, at different concentrations (2.5&5µg), prior to infection with secondary hydatid disease. Results show that neutrophils express a different affinity towards TFs of different concentrations and different sources (P and HCF). Phagocytosis was higher in +ve control compared to –ve control, and was higher at concentration 2.5µg compared to 5µg in P and was the other way around in HCF at 5µg, indicating that there is a correlation between concentration of TFs, their source and their effect. | ||
| Keywords | ||
| toxin fraction; hydatid; Phagocytosis; mice | ||
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