| The mosquitoes, Culex pipiens is one of the most important insect as a vector for pathological parasite and microbial pathogens, which infect human, This keep it in front of pathogenic vector. Which require special programs for controlling it. This study focused on the effectiveness of caffeine extract at the concentration: 1000, 2000, 3000, 4000 and 5000 ppm on the immature stages of Culex pipiens molestus. The result showted an increasing in larval accumulated mortality rate by increasing concentration, which was (46.67, 66.67, 80.0, 86.67 and 96.67)% respectively. In non-accumulated mortality rate the first larval instar more sensitive in compared with 4th larval instar, where the mortality rate was (30.42,48.57,66.30,70.42 and 73.71)% for first larval instar respectively and was (11.30,17.42,23.85,28.65 and 30.76)% for 4th larval instar respectively some pupal mortality and failed in adult Eclosion from exuvia have been seen an this correlated with increasing of concentration |