The aim of this study was undertaken the effect of number of calving on incidence of puerperal metritis and using many uterine therapy to see their effect reproductive performance in dairy cows in middle of Iraq. The study was conducted on 150 cows in alwahda station of dairy cows and milk production that located south- west Baghdad city during the period march1999 until march 2001, the study included 150 cross breed Holstein- Friesian cows which divided to three groups upon number of calving, every group contain 50 cows ,the first group had 1-2 calving contain 30 cows (60%) suffered from puerperal metritis, second group had 3-4 calving contain 20 cows (40%) suffered from the condition, while 22 cows (44%) 0f third group affected of puerperal metritis, there was significant difference (P<0.05) between first group and second, third groups, the infected cows had treated, first group were given pen-strep (20 ml + 250 ml distal water) injection to uterine, second group were treated by intrauterine injection of lugol solution (5o ml 2%), the third group were given metrgit (tetracycline500 mg+estradiol 5 mg), the percentage response were (60%,75%, 63.3%) for all groups respectively and there was significant difference (P<0.05) between second group and others groups. The open days and number services for conception (165,122,130 days), (2.8, 2.4,2.5) for all groups respectively, there was significant difference (P<0.05) between first group and other groups in open days, there was no significant difference in numbers services for conceptions in all groups. It was concluded that increase on incidence of puerperal metritis in cows had 1-2 calving with increase days open compared with others cows ,and lugol iodine solution gives the best results for treatment of puerperal Metritis in cows compared with the other treatment |