Histological Effects of fasting and subsequent refeeding on thyroid follicles of rabbits morphometric analysis

Ghanim Abdulla, Ali

	Histological Effects of fasting and subsequent refeeding on thyroid follicles of rabbits morphometric analysis
Tikrit Journal of Pure Science
Article 1, Volume 16, Issue 2, 2011, Pages 12-16
Author
Ali Ghanim abdulla
Abstract
The effect of fasting and refeeding on thyroid gland had been studied histologically on (20) local breed rabbits. They were subdivided into (2) groups, (10) rabbits as control (fed) group, (10) rabbits as experimental( fasted) group. The control group was fed vegetables, while the experimental group was fasted for (48) hours, and then provided food for (4) hours, the results were : insignificant reduction in diameter of thyroid follicles, amount of colloid, & height of follicular epithelium in the experimental group, in which the diameter of thyroid follicles of control group was (21.1±4.7), while for experimental group was (19.5±4.42), the amount of colloid in control group was (18.2±3.8), and for experimental group was (15.6±5.2), the height of follicular epithelium in control group was (2.6±0.63), and for experimental group was (2.13±0.48). there was a significant increase in the number of C- cells in experimental group which was (3.31±1.9), while it was (1.2± 1.17) in the control group. The reduction in thyroid follicles, thyroid colloid, & height of follicular epithelium occur as a result of changing in feeding behavior which causes decrease in iodine food incorporation, and decrease in level of 5- monodeiodoinase a mediator of T3 and T4. The increase in the number of C cells happened as a protective mechanism to save the skeleton from excessive bone resorption.
Keywords
Thyroid follicles; fasting; refeeding

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