Influence of Thyroxine and Thyrotropin on Some Biochemical Parameters in the Umbilical Cord Blood Serum of Healthy Neonates

	Influence of Thyroxine and Thyrotropin on Some Biochemical Parameters in the Umbilical Cord Blood Serum of Healthy Neonates
Tikrit Journal of Pure Science
Article 1, Volume 14, Issue 1, 2009, Pages 285-290
Abstract
The means and standard deviations of the body weight and eight biochemical parameters of the umbilical cord blood serum were determined for 30 (15 males and 15 females) healthy neonates. The means were (110.40  17.29) nmol/L for thyroxine (T4) hormone; (5.751.45) mU/L for thyrotropin (TSH), (41.00  6.40) mg/dl for glucose, (4.72  0.93) mg/dl for uric acid and (2.73  0.16) Kg body weigh. The activity of the enzymes alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) on the other hand, were (8.572.14),(20.21 7.88), (117.58  28.64) and (184.00  26.43) IU/L respectively. None of these parameters was affected by sex except the ALP which was a little bit higher in males (129 31.01) IU/L than in females (104.62  20.32) IU/L. Correlation analysis between pairs of parameters revealed a positive significant association between T4 and TSH (r=0.590); between TSH and glucose (r=0.539) and between the body weight and glucose (r=0.576). These significant correlations support what was expected for a relation between these hormones and the other biochemical parameters starting from birth and lasting for rest of life

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