Isolation and studing the effect of proteinous and non- proteinous fractions of Pea fruit plant (Cicer arietinum L.) exposed rabbits to oxidative stress

Alsaadon, M.B.

	Isolation and studing the effect of proteinous and non- proteinous fractions of Pea fruit plant (Cicer arietinum L.) exposed rabbits to oxidative stress
Tikrit Journal of Pure Science
Article 1, Volume 13, Issue 1, 2008, Pages 150-157
Author
M.B. Alsaadon
Abstract
This study was included prepare a cold aqueous extract of fruit plant . The study also comprised the isolation and study the proteinaceous compounds, One of the techniques used isolation was the gel filtration technique which was isolated two compound A (40935 ) Dalton and B (5495 ) Dalton. Extracts were administrated interaperitioneally. After one week from the treatment the results were indicated that the crude aqueous non proteinaceous extract, proteinaceous precipitate and proteinaceous compound (A) at the doses of (750, 25.98, 1.54) mg/Kg body weight, which were caused a significant decrease (P < 0.05) in serum glucose, total cholesterol (TC), triglyceride (TG) low density lipoprotein-cholesterol (LDL-C) levels and malondialdehyde (MDA) content of the liver , kidney and heart tissues , with an associated significant increase (P < 0.05) in serum high density lipoprotein-cholestesrol (HDL-C) level and glutathione (GSH) level in liver, kidney and heart tissues in exposed rabbits to oxidative stress . The proteinaceous compound (B) at the dose of (1.48) mgkg body weight produced a significant increase (P< 0.05) in serum glucose level ,while the non-proteinaceous precipatite at the dose of (724) mgkg body weight which had no changes significant (P< 0.05) on glucose level in exposed rabbits to oxidative s

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