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Effect of extract of the Chinaberry tree Melia azedarach L. on the testes of Rats ( Rattus norvegicus ): Histopathological study | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 13, Issue 2, 2008, Pages 249-251 | ||
| Author | ||
| Hamad J. Jumaa | ||
| Abstract | ||
| The Present study was conducted to investigate the histopathological changes Ruttus norvegicus after treatment with extract of mature fruit of M. azedarach L. Adult male rats treated with dose rate of 25 gm / kg. B.w. exhibited histopathological alterations in testes indicating atrophy of some seminiferous tubules , degeneration and necrosis of spermatogenic cells , exfolation of spermatocytes to tubule cavity. No remains of some tubules only basement membrane and few accumulation of spermatocytes. while the dose rate of 50 gm / Kg. B. W. caused absence of all spermatogenesis cells and sertoli cells as well as the absence of spermatozoa (sperms), hyperplasia in interstitial cells (Leydig cells) congestion of blood vessels , and accumulation of edematous in interstitial tissue. | ||
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