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Measurement of Cytokines Concentration (IFN- γ and IL-10) in the Serum of Cutaneous leishmaniasis patients. | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 12, Issue 1, 2007, Pages 55-61 | ||
| Author | ||
| Hussein S. Aswed Al-Obaidi | ||
| Abstract | ||
| A total of 107 patients with cutaneous leishmaniasis (CL) were included in this study. They were 57% males, while 43% females. Their ages ranged from 1-60 years old. Estimation of IL-10 and IFN- concentration in patients and control groups revealed the mean level of IL-10 and IFN- was significant increased in patients groups (P < 0.05) in comparison with control groups. Even that the mean level of IFN- in patients groups was less than the mean level of IL-10, since the mean of IL-10 in patients groups were 28.33 ± 0.36 Pg/ml, 36.76 ± 0.27 Pg/ml and 2.92 ± 0.28 Pg/ml respectively, while it was 0.04 ± 0.002 Pg/ml, 0.08 ± 0.008 Pg/ml, 0.027 ± 0.001 Pg/ml in control groups respectively, while the mean of IFN- level in patients groups were 6.8 ± 0.06 Pg/ml, 6.0 ± 0.008 Pg./ml and 0.52 ± 0.008 Pg/ml in patients groups respectively, while it was 0.06 ± 0.002 Pg/ml, 0.06 ± 0.008 Pg/ml and 0.005 ± 0.002 Pg/ml in control respectively. | ||
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