Effect of Giardia lamblia on some biochemical changes of the human

G. S, Yahya

	Effect of Giardia lamblia on some biochemical changes of the human
Tikrit Journal of Pure Science
Article 1, Volume 12, Issue 1, 2007, Pages 29-32
Author
Yahya G. S
Abstract
The study was carried out in Kirkuk province from period 15th of October 2005 to 1st of June 2006. The main aim of the study was to measure the adverse effects of giardiasis on some biochemical tests of the host. For this purpose a total of 997 stool samples were collected from children aging from one 1---- 12 years, giardia was diagnosed by using double wet preparation of 0.85 % of normal saline to detect trophozoites & lugols iodine 1% to detect cystic stages, all positive cases were confirmed by using concentration method( flotation technique Zinc sulphate ZnSo4 solution). After detecting positive cases, venous blood samples were drawn from infected children (study group) and healthy children (not infected) they consider as a control group, to assess the effect of giardiasis on some biochemical tests of the host (random blood sugar, serum (S.) Cholesterol, serum total protein, serum albumin, serum copper & serum magnesium)were chosen . Biochemical tests were determined using special enzymatic kits purchased from local companies in the city. The overall rate of giardiasis was 13.23 % which was distributed in 132 stool samples. Stool examination by using concentration method (Flotation technique using ZnSo4 solution) shows high efficacy in demonstrating giardiasis (13.23 %) more than using wet preparations (9.62 %) the relation ship was significant (P<0.05). Sera of infected children with Giardia lamblia Shows decreasing in mean value of blood sugar ( 91.3 mg/100 ml), S. cholesterol (143 mg/100ml), S. total protein (6.43gm/ml), S. albumin(3.51 gm/100ml ) and S. magnesium, (1.55 mg/100 ml) P<0.05 compared to sera of non infected (control group), which shows (99.7 mg/100ml), (184.4mg/100ml), (7.47gm/100ml),(4.39gm/100ml) and( 2.12 mg/100ml) for blood sugar, S. cholesterol, S. total protein, S. albumin and S. magnesium respectively P>0.05. While S. globulin & S. copper mean values were within normal P>0.05.

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