- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Treatment of Systemic Candidiasis in Rats with Water Extract of Thymus Vulgaris L. | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 6, Issue 2, 2009, Pages 235-242 | ||
| Author | ||
| Fatima M. Abas | ||
| Abstract | ||
| Water extract of leaves from Thymus vulgaris L.was tested in vitro for its antifungal activity against pathogenic Candida albicans , using well diffusion method . Extract of T. vulgaris revealed a potent antifungal activity against C. albicans at 20% concentration . An experimentally – disseminated candidiasis was induced into a group of BALB/c rats by intravenous inoculum of C. albicans (0.2 ml of 3×10 5 cell / ml) and observations were made and recorded for a period of 30 days . Shivering, dullness , ataxia with a progressive decrease in body weight were observed in all the infected rats. White nodular abscesses were seen in kidney after 3 days of injection. Treatment of infected rats with the plant extract (0.5 ml administered orally for 14 days) caused an increase in the weights of the rats when compared with control animals. | ||
|
Statistics Article View: 111 PDF Download: 78 |
||