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The Biological Effects of Thymus vulgaris Extracts and its Ingradient Against Some Bacteria and its Synergism Between the Active Material with Antibiotics | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 11, Issue 2, 2006, Pages 85-92 | ||
| Author | ||
| Khider Dawood Sulayman | ||
| Abstract | ||
| This study was indicated the biological activity of Thymus vulgaris extract involving its oil active ingredient against six bacterial species: Staphylococcus aureus, Streptococcus pyogenes, Bacillus subtilis, Shigella flexneri, Proteus inirabilis, Pseudomonas aeruginosa. The ethanolic extract was showed more bacterial inhibition against the bacterial species except Pseudomonas aeruginosa. The acetonic extract was showed similar alcoholic extract effects. The Thymus vulgaris oil extract showed comparable inhibition effect against the all bacterial studied. It showed maximum inhibition effect at 0.1 cm3/cm3 of about 31 mm against S. pyogenes. The active material (Thymol) showed maximum inhibition activities toward S. Pyogenes, S. aureus compared to the control and medium activity to the antibiotic Ciprofloxacin. The radius of the inhibition zone against S. pyogenes of 200 mg/ml is about 34 mm. While against P. aeruginosa of the same concentration is about 19 mm. The sensitivity measurements of the antibiotic in the presence of the active material in which the bacterial resistance was measured before using the Thymol oil extract. Four antibiotics were used namly Ampicillin, Chloramphenicol, Cephalosporin and Trimethoprim. It was found that S. aureus became more sensitive toward Ampicillin, Trimethoprim and Cephalosporin in the presence of the active material (Thymol) while P. aeruginosa was still in resistance to Chloramphenicol, Cephalosporin and Ampicillin in the present of (Thymol), while it became more sensitive to the antibiotic Trimethoprim in the presence of the active compo | ||
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