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Determination of Codeine phosphate (CP) &Trifluoperazine hydrochloride (TFPH) By Flow injection- Chemiluminescence | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 11, Issue 2, 2006, Pages 243-246 | ||
| Author | ||
| Suham Towfig Amine | ||
| Abstract | ||
| This study involves the application of flow injection- chemiluminscence (C.L) technique for determination of codeine phosphate (CP) and Trifluoperazine hydrochloride (TFPH)drugs .(CP)was found to inhibit the C.L of the system of Luminol as a reagent , cobalt ion as a catalyst and hydrogen peroxide as an oxidizing agent whereas (TFPH)exhibit an increase for C.L signal. The calibration curve for (CP) as active material obeys lambert-bear law in the range (25-250) ppm,with detection limit 2.08ppm,R=0.9983, Recovery( Rec)=102% , Relative error ( E%)=-2.281 . The calibration curve for(TFPH) ) as active material is linear in the range (1-16)ppm with detection limit 0.0832ppm ,R=0.9990 ,Rec=98.3% , E%=2.0. This method was succefully applied to the determination of (CP) in Plumocodine and (TFPH) in Salabid pharmacetucal preparations with percent recovery of 101.6% &106% respectively . | ||
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