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THE EFFECT OF SOME EXTRACTS ISOLATED FROM PHASEOLUS VULGARIS AND VIGNA SINENSIS FRUITS IN MICE EXPOSED TO OXIDATIVE STRESS | ||
| AL-TAQANI | ||
| Article 1, Volume 21, Issue 2, 2008, Pages 0-0 | ||
| Abstract | ||
| This work included study the effect of some aqueous extracts of Phaseolus vulgaris and Vigna sinensis plants on glutathione (GSH) and malondialdehyde (MDA) level in mice exposed to oxidative stress using hydrogen peroxide H2O2 (% 0.5). Seven doses intraperitoneal injection of 77 mg / kg body weight of these isolates were used in this study .The results showed that mice treated with hydrogen peroxide orally a showed significant increasing ( glucose , cholesterol and total lipids ) level when compared with control group . While the results of injected with extracts which were obtained from plants for mice exposed to oxidative stress indicated that glutathione level arise significantly especially when the proteinous compound (A) for the cold extract of Vigna sinensis fruits was injected . Also the results revealed that malondialdehyde ratio decreased clearly when the same extracts especially compound (A) was injected . therefore we can suggest that the compound (A) has similar effect to that of insulin in decreasing (MDA) level and increasing (GSH) level . Finally we concluded that most of extracts isolated from fruits of both Phaseolus vulgaris and vigna sinensis plants (especially compound (A)) have antioxidant effect in mice exposed to oxidative stress . | ||
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