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Adenosine Deaminase Activity in Blood Serum of Pregnant Women Infected by Toxoplasmosis in Nenavah Governate | ||
| Tikrit Journal of Pure Science | ||
| Article 1, Volume 11, Issue 1, 2006, Pages 235-240 | ||
| Author | ||
| Muna H. Janker | ||
| Abstract | ||
| Adenosine deaminase E.C.3.5.4.4 activity was studied in blood serum of pregnant women infected by Toxoplasmosis caused by Toxoplasma gondii as one of the causes of abortion , aged 18 to 44 years compared with normal pregnant women. The results obtained showed that the normal adenosine deaminase specific activity was 14.7 ± 0.98 n mole of adenosine deaminated per min. per mg protein. It appeared that the activity increased with increasing the titer of infection , it had been showed that at 1/80 and 1/60 cases, the activity was 53.68 ± 16.6 and 60.03 ± 5.05 respectively, while the mean value of activity in titers 1/320 and 1/640 was 77.99 ± 12.61 and 89.86 ± 5.05 respectively. The results showed that the percentage of infection which was obtained increased with the increase in the enzyme activity in abortion recorded in the first trimester which was 80% and there opposite proportion between the enzyme activity and the number of abortion. The above results may consider as a novel diagnostic tool for Toxoplasmosis by using adenosine deaminase activity. | ||
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