Ayoub, M. (2006). New Method for the Synthesis of 4-Methoxy-6-aryl-2-pyrones; Synthesis and Bromination of 3-Methoxy-5-aryl-(2E,4E)-2,4-pentadienoic Acids. , 11(1), 46-51.
M.T. Ayoub. "New Method for the Synthesis of 4-Methoxy-6-aryl-2-pyrones; Synthesis and Bromination of 3-Methoxy-5-aryl-(2E,4E)-2,4-pentadienoic Acids". , 11, 1, 2006, 46-51.
Ayoub, M. (2006). 'New Method for the Synthesis of 4-Methoxy-6-aryl-2-pyrones; Synthesis and Bromination of 3-Methoxy-5-aryl-(2E,4E)-2,4-pentadienoic Acids', , 11(1), pp. 46-51.
Ayoub, M. New Method for the Synthesis of 4-Methoxy-6-aryl-2-pyrones; Synthesis and Bromination of 3-Methoxy-5-aryl-(2E,4E)-2,4-pentadienoic Acids. , 2006; 11(1): 46-51.

New Method for the Synthesis of 4-Methoxy-6-aryl-2-pyrones; Synthesis and Bromination of 3-Methoxy-5-aryl-(2E,4E)-2,4-pentadienoic Acids

Tikrit Journal of Pure Science
Article 1, Volume 11, Issue 1, 2006, Pages 46-51
Author
M.T. Ayoub
Abstract
Synthesis approaches to the 4-methoxy-6-aryl-2-pyrones (11) are described in which the key step is cyclisation of 3-methoxy-4,5-dibromo-5-aryl (2E)-pentenoic acids (9) with triethylamine in benzene followed by oxidation with DDQ. The acids, 3-methoxy-5-aryl-(2E,4E)-2,4-pentadienoic acid (5) are prepared from the reaction of ethyl 3-methoxy-(2E) butenoate (4) with aldehydes in the presence of sodium hydride. Bromination of these acids with bromine gave selectively (9). The stereochemistry of cyclisation reaction are described..
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