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Changes in creatine kinase values in the serum of mothers of Duchenne muscular dystrophy patients | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 5, Issue 1, 2008, Pages 96-99 | ||
| Authors | ||
| Mohammad Obai; d Al-Muhammady; d Merza Al-Aaraji; ; Ahlam K. Abood | ||
| Abstract | ||
| Duchenne Muscular Dystrophy(DMD) is a sever x-chromosome linked degenerative disease of muscles affect boys due to mutations at a specific locus on the short arm of the X-chromosome. In the early stages of disease the affected young boys show loss of strength in their proximal muscles leading to waddling gait, to difficulty in standing up and eventually to very sever weakness. Serum creatine kinase (CK) levels were measured in nineteen women who are mothers of DMD patients and compared with another serum CK of nineteen women with negative history of DMD(control group). The results indicate that serum CK levels of patient ’s mothers are significantly higher than serum CK values of control group, and the serum CK values have markedly increased in52.1% of the patient’s mothers, this lead to conclusion that 52.1% of these patient’s mothers are carriers for disease and 47.9% are due to new mutations which may caused by the environmental factors. | ||
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