Study of Some Physiological and Biochemical Changes in Patients with Chronic Renal Failure (CRF) Undergoing Hemodialysis in Al-Najaf Governorate

	Study of Some Physiological and Biochemical Changes in Patients with Chronic Renal Failure (CRF) Undergoing Hemodialysis in Al-Najaf Governorate
Magazine of Al-Kufa University for Biology
Article 1, Volume 4, Issue 1, 2012, Pages 36-44
Abstract
The current study aimed at assessing some physiological and biochemical changes in patients with chronic renal failure (CRF) undergoing hemodialysis . It was achieved at Al-Hakim general hospital in the Holy city of Najaf during the period from 172010 to 112011 , (100) cases of both sexes were monitored including (75) patients with chronic renal failure and a control group of (25) healthy persons . The statistical analyses revealed a significant decrease (p<0.05) in the concentration of hemoglobin (Hb), packed cell volume (PCV) , platelet count, and the total leucocytes count in the patients with CRF compared with the control group . The differential leucocytes count exhibited a significant increase in the percentage of neutrophils, monocytes and eosinophils ; while the percentage of lymphocytes decreased significantly (p<0.05) in the patients group The biochemical investigations revealed a significant increase (p<0.05) in the concentration of serum triglycerides and the activity of alkaline phosphatase (ALP) , and a significant decrease (P<0.05) in the concentration of serum high density lipoproteins (HDL) and the activity of aspartate & alanine transaminases (AST & ALT) in the CRF patients by comparing with control group . In summary, the current study came to that chronic renal failure had affected physiological and biochemical parameters under study .

Statistics Article View: 106 PDF Download: 38