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The humoral mucosal immunity of urinary tract kelbsiella infections in menopausal women | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 5, Issue 2, 2008, Pages 198-205 | ||
| Authors | ||
| Shnawa i.m.s; Hamza h.j | ||
| Abstract | ||
| Seventy – one menopausal women patient (MWP) with urinary tract infections (UTI), thirty - two adulthood women patients (AWP) with UTI and twenty normal women subjects (NWS) were the study groups. Pyuria but not haematuria via examination of urine sediments. Kelbsiella like colony morphotypes were noted on blood agar and Mac (on key agar, in single and mixed infection patterns. K. pneumoniae and, K. oxytoca , were identified as uropathogens. Klebsiella antigenic epitopes can be of B cell and of the Th2 dependent types activating mucosal humnal immnal immune responsce in the urinary tract during Klebsiella infections. Lower mucosal antibody titers (4-16) were noted among MWP than that of AMP (16-64). This may attributed to local costimulatory signals, activation of suppresser T cells and disturbance of the Th1/Th2 activities leading to production of low activity and affinity antibodies. | ||
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