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In vitro and In vivo evaluation of antimicrobial effect of leaves Ocimum basilicum of ethanolic extract against Staphylococcus aureus | ||
| Al-Anbar Journal of Veterinary Sciences | ||
| Article 1, Volume 4, Issue 2, 2011, Pages 67-75 PDF (78.45 K) | ||
| Author | ||
| N. Z. Yahya | ||
| Abstract | ||
| The well diffusion method, Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) were implemented to evaluate the antibacterial activity of Ocimum basilicum against Staphylococcus aureus. The growth of S.aureus was inhibited after application of Ocimum basilicum at concentrations of 0.34 to10.96 mg/ ml in the test of MIC and MBC. The greater inhibition zones (12.2 ± 0.3 to 20.0 ± 0.2 mm) were observed due to O. basilicum at concentrations of 20 to 100 mg/ml in the well diffusion test respectively. Ocimum basilicum. Extract enhanced wound healing and disappearance of inflammation signs with regrowth of hair at the site of the experimentally made incision inoculated with Staphylococcus aureus. Antibacterial activity of Ocimum basilicum extract could be attributed to some active ingredients having the ability to complex with extra cellular and soluble protein and to complex with bacterial cell wall disrupting microbial membranes | ||
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