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Role of Testosteronthiosemicarbazone as an Antibacterial Agent | ||
| Engineering and Technology Journal | ||
| Article 1, Volume 28, Issue 23, 2010, Pages 6703-6708 PDF (137.4 K) | ||
| DOI: 10.30684/etj.28.23.8 | ||
| Authors | ||
| Abbas A. Al-Janabi; Suhad A. Ahmed; Huda A. Hussein | ||
| Abstract | ||
| A ligand of testosteronthiosemicarbazone was prepared, the chemical characteristics of this ligand are: yellow powder, soluble in alcohol and its melting point is 100 – 102 °C. The sensitivity of some species of pathogenic bacteria including Escherichia coli, Proteus vulgaris, Klebsiella pneumonia, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus feacalis to different concentrations of prepared testosteronthiosemicarbazone (0.05 g/ml, 0.1 g/ml, 0.25 g/ml, 0.5 g/ml, and 1 g/ml) was tested to find out the role of testosteronthiosemicarbazone as an antibacterial agent. The experimental results of bacterial sensitivity to different concentrations of testosteronthiosemicarbazone, showed a significant sensitivity of all tested bacteria to this ligand at concentration starting from 0.5 g/ml, to 1 g/ml except Pseudomonas aeruginosa, and Streptococcus feacalis which they exhibited their significant sensitivity to the ligand at concentration starting from 0.25 g/ml, and 1 g/ml respectively. | ||
| Keywords | ||
| testosteronthiosemicarbazone; ligand; chelating agent; antibacterial agent | ||
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