- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Development of Spectrophotometric Method for Determination of Chlorpromazine-Hydrochloride in Pharmaceutical Preparations Via Use Ion-Exchange to Overcome the Interfering Ions | ||
| Baghdad Science Journal | ||
| Article 1, Volume 5, Issue 3, 2008, Pages 362-370 | ||
| Author | ||
| Bushra Basheer Kasim | ||
| Abstract | ||
| In this scientific piece of research work, chlorpromazine CPZ (a psychaity drug) was determined spectrophotometrically using micro amount of reactant. In addition to micro amount of spectrophotometric reagent (400 l). Various oxidizing agents were tested, including periodate, iodate, bromate, ferric nitrate, ferri cynate and persulphate. Oxidation reactions of the active ingradient (2,10-disubstituted phenothiazine) was used for the determination of CPZ in the presence of ferric nitrate. Detailed study of all chemical and physical parameters were studied. Ion-exchange columns were used to overcome the interfering ions. Percentage linearity was 99.86 for 0.04-8 mM CPZ, L.O.D. was 110-6M. Repeatabilety was better than 1.5%. The established results were followed to determine in some drugs. | ||
|
Statistics Article View: 170 PDF Download: 100 |
||