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THE INFLUENCE OF ADJUVANT AND IMMUNOGENIC SUBSTITUTION FOLLOWING IMMUNIZATION WITH DIFFERENT ANTIGEN | ||
| AL-TAQANI | ||
| Article 1, Volume 19, Issue 1, 2006, Pages 17-22 | ||
| Authors | ||
| Asmaa S. Al; | ||
| Abstract | ||
| The nature of the antigen and the presence of the adjuvant are the major factors, which influence the level of then immune reactivity following immunization. This study examines the quantity and isotype of antibody produced in rabbit immunized with different antigens in combination with different adjuvant. The primary and secondary antibody levels to various antigens in Freund’s complete adjuvant (FCA) and alum adjuvant were compared between the groups. Results using ELISA assay show that animals immunized with antigens in adjuvant produced lower level (p< 0.05) of the antibody compared with animals that were immunized with direct antigens in the marginal vein. The antibody titer was higher significantly in animals given oil-emulsion adjuvant than the alum. | ||
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