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Synthesis of Some Quinazolines and Imidazolo-[1,5-a]-3,1-benzoxazine-4-one Derivatives | ||
| Rafidain Journal of Science | ||
| Article 5, Volume 19, Issue 1, 2008, Pages 37-44 PDF (0 K) | ||
| DOI: 10.33899/rjs.2008.42268 | ||
| Author | ||
| Nameer S. Ezzat | ||
| Abstract | ||
| Some substituted N-methylene-2-(3,1-benzoxazonyl-4-one) amide (3a-c) were prepared from reaction of acetic anhydride with N-acyl anthranilic acid (2a-c) was synthesized from anthranilic acid with acyl glycinyl chloride. Treatment of (3a-c) with POCl3 gave imidazolo-[1,5-a]-3,1-benzoxazin-4-one (4a-c). Quinazoline derivatives (6a-c) were prepared by reaction of methyl anthranilate with imidoyl chloride, the resulting esters were then converted to the hydrazides (7a-c). The synthesized compounds were identificated by IR and UV spectra. | ||
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