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Phytolectin Induced Experimental Lapin Immunomodulation | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 3, Issue 3, 2006, Pages 194-199 | ||
| Authors | ||
| Ibrahim M.S. Shnawa; Ali M.S. Alkhafaji | ||
| Abstract | ||
| The plant seed extracts of Cucumis. sativus and Citrullus. colocynthus are containing glycoprotein molecules described to be of lectin characters . These lectins were used as possible immunomodulant . The test immunogen was Mycobaterium tuberculosis PPD and the test immune system was the rabbit with the aim of proving of any immunomodulating effects . The C. sativus lectin (Csl) stimulate the secondary humoral immune response and produce leucocyte inhibitory cytokines in primary , secondary cell mediated immune responses as well as augmentation of skin DTH reaction in both primary and secondary responses. The C.eulocvnthus lectin (Ccl) was stimulating to primary and secondary humoral immune responses as well as it stimulate production of Leucocyte inhibitory cytokines (LIF) both primary and secondary cell mediated immune responses. It was however, inhibiting to skin DTH reactions in both primary and secondary responses Thus Csl and Ccl are of immunomodulating potential in rabbits, Immune system affecting both humeral and cellular arms. | ||
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