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The Use of Intralesional Metronidazole in the Treatment of Cutaneous Leishmaniasis | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 3, Issue 3, 2006, Pages 260-264 | ||
| Authors | ||
| Huda Hadi Al-Hassnawi; Mohammed Sabri Al-Saeed; Hadi Fadhel Al-Yassari; Suhayer Isa Al-Qaysi | ||
| Abstract | ||
| Seventy patients (70 lesion , 48 dry, 22 wet) with typical acute cutaneous leishmaniasis in mirjan teaching hospital in Hilla city from January to May,2004 were included in this project. Thirty eight(55%) of them were females and thirty two(45%) were males .Their ages ranged from 1-50 years, 53 patients had few lesion (1-5 lesions) 75%, 17 patients had multiple lesions above (5 lesions) 25%. Duration of lesions was 2 weeks - 6 months. The patients were divided into 3 groups, the first group included 33 patients how were given 1% metronidazole solution intralesionally. The cure rate was 75% in one to two injections required for complete cure, 1-2 weeks intervals between each injection,12% in the third injection, 9% in the fourth injection, and 4% in the fifth injection. Each patient followed up for 6 weeks. The second group included 20 patients, metronidazole was given orally in a dose of 200 mg , 3 times daily for 4 weeks, no apparent clinical improvement was observed. The third group included 17 patients how were given placebo treatment as a control for this study. No clinical improvement was observed during 6weeks follow up. | ||
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