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Mucoepidermoid Carcinoma of Salivary Gland Origin: Study of Clinico Pathological features and prognosis | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 2, Issue 3, 2005, Pages 272-282 | ||
| Authors | ||
| Ali H.AL-Timimi; Ali.AL- Katib | ||
| Abstract | ||
| Most cases of mucoepidermoid carcinoma are located in the parotid gland. This lesion represents one of the most common malignant salivary gland tumor .We have studied 54 cases of mucoepidermoid carcinoma (MEC) originating in major and minor salivary glands that were admitted to Hilla Teaching Hospitals ,the Department of Surgery, Medical collage, between 1991 and 2003. Following the methods of Auclair and Goode, a quantitative grading system was used. The relationships between clinical and pathologic characteristics and survival rate were investigated. The results revealed that 13(44%) cases located in MASG and 10 (39%) cases in MISG were categorized as high-grade tumors. In patients with MASG tumors, the 5-year disease-free survival rate was 22.5% when the tumor was high grade and 97.0% if the tumor was low grade (P < .0001). For patients with a tumor of the MISG, the percentages were 35.3% for high-grade and 80.0% for low-grade tumors (P = .0066). Our conclusions confirms that in mucoepidermoid carcinoma, tumor grade, subdividing cases into low and high grade by using the criteria delineated by Auclair and Goode, correlates well with prognosis. | ||
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