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The Significance of a-L-Fucose as Biomarker in Cell Proliferation | ||
| Medical Journal of Babylon | ||
| Article 1, Volume 2, Issue 3, 2005, Pages 311-317 | ||
| Author | ||
| Hamid Ghafory Hassan | ||
| Abstract | ||
| A methylated sugar pentose (a-L-Fucose) was investigated in 12 abnormally proliferated cells represents 331 cases, These were includes 95 leukaemia, 150 normal pregnancy, 50 type-II DM, 10 thalassaemia, 2 Hodgkin` s disease, 3 colone cancer, 2 stomach cancer, 4 multiple myeloma, 5 pancreas cancer, and 10 breast cancer. Data obtained were compared with that of healthy controlled objects (100 samples). The study was comprehensive the determination of the clinical parameters related, i.e, total protein, protein bound fucose, protein bound Hexoses, and total calcium in an attempt reflecting their clinical values as biomarkers. Ratios concerning the distribution of total fucose and related parameters were compared to the total protein. Degree-fold increases were also determined concerning total fucose in proliferative cells to that of normal values. | ||
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