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A Comparative Study between Healthy and Reversible Obstructive Uropathy Patients under Anesthetic Muscle Relaxation by the use of Atracurium Besylate | ||
| Medical Journal of Tikrit | ||
| Article 1, Volume 2, Issue 112, 2016, Pages 76-82 | ||
| Author | ||
| Hosam AL-Deen S. Mohamad Saeed | ||
| Abstract | ||
| This study was designed to identify the correlation among the duration of action and the degree of muscle relaxation of atracurium by the use of a peripheral nerve stimulator in healthy surgical patients and in patients need surgery due to reversible obstructive uropathy . The total number of patients was 33.They were divided into two groups, group I (22 patients) and group II (11 patients) All the surgical operations included in the research, last for not less than 75 minutes . In both groups I and II Atracurium was given as a bolus intravenous injection in a dose of 0.5 mg/kg .The bolus dose of the muscle relaxant was followed by 5 i.v injections (0.1 mg/kg)for each top up dose according to the monitored neuro-muscular transmission by the peripheral nerve stimulator. In the first group the duration of action of the bolus dose was 21.87±3.03 minutes as determine by positive TWR and positive T3 by TOF. The duration of action of 1st ,2nd ,3rd and 4th intravenous doses administered after the bolus dose were 13.5±2.08,12.37±2.40,13.19±2.84 and 13.28±1.40 minutes respectively. In the second group ( patients with reversible obstructive uropathy) who received the bolus dose of atracurium followed by 5 intravenous doses ,the duration of action of the bolus dose was 19.79±2.33 minutes ,while the duration of action of 1st ,2nd ,3rd and 4th intravenous doses administered after bolus dose were 12.89±0.76,13.28±1.45,12.28±2.87 and 13.81±1.88 minutes respectively. | ||
| Keywords | ||
| A Comparative Study between Healthy and Reversible Obstructive Uropathy Patients under Anesthetic Muscle Relaxation by the use of Atracurium Besylate; Atracurium | ||
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