Biochemical Study of Leptin and Insulin Hormones and their Relationship to Concentrations of Some Minerals in  Diabetic Patients

Th. Younis, Nawal; A. Al-chalabi, Kusia; A. Al-Allwsh, Thikra

doi:10.33899/rjs.2006.43467

	Biochemical Study of Leptin and Insulin Hormones and their Relationship to Concentrations of Some Minerals in Diabetic Patients
Rafidain Journal of Science
Article 4, Volume 17, Issue 8, 2006, Pages 29-40 PDF (0 K)
DOI: 10.33899/rjs.2006.43467
Authors
Nawal Th. Younis; Kusia A. Al-chalabi; Thikra A. Al-Allwsh
Abstract
The research, involved Biochemical study of leptin, Insulin and their relationship to some minerals in diabetic patients (Type I and Type II ) compared with normals . The results demonstrated that the normal mean of Leptin hormone in human blood serum (19.5  5.6 ng / ml), and body weight affected Leptin concentration, while the results demonstrated a significant decrease in the level of Leptin and Insulin levels in serum of type I diabetic Patients in comparison with control and a significant difference in the mean levels of Leptin and Insulin between type I and II . The results also demonstrated a significant decrease in the means of Potassium and Magnesium concentration in patients type I compared with control group, while non significant decrease of Sodium and Zinc in diabetic Patients type I and II compared with control . Correlation coefficients between Leptin, Insulin hormone and some minerals of diabetic patients showed that Leptin hormone has a positive linear relationship with Magnesium and Zinc in control and diabetic patients type I and II, while Insulin hormone has a positive linear relationship with Magnesium and Zinc in control and diabetic patients type II, and showed a positive linear relationship with Magnesium in diabetic patients type I. Also the results demonstrated a positive linear relationship between Leptin, Insulin hormone and Potassium in control group .

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