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Synthesis of Schiff Bases of Benzaldehyde and Salicylaldehyde asAnti-inflammatory Agents | ||
| Iraqi Journal of Pharmaceutical Sciences | ||
| Article 1, Volume 16, Issue 2, 2007, Pages 5-11 | ||
| Author | ||
| Tagreed N. Omar | ||
| Abstract | ||
| Three Schiff bases from Benzaldehyde and Salicylaldehyde have been synthesized (A, 1and 2) and two of them (1and 2) have been tested for anti-inflammatory activity. The p-aminobenzene sulfonamide has been synthesized from acetanilide through the addition of excess chlorosulfonic acid then concentrated ammonia solution; Schiff base of this derivative (2) exhibited good level of activity against egg-white induced edema in rat hind paw, while the other tested derivative exhibited no activity. | ||
| Keywords | ||
| Schiff bases; sulfonamide derivatives; salicylaldehyde | ||
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