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Study on Adherence of Pathogenicity of Moraxella catarrhalis in the Respiratory Tract of Patients | ||
| Rafidain Journal of Science | ||
| Article 14, Volume 17, Issue 10, 2006, Pages 147-158 PDF (0 K) | ||
| DOI: 10.33899/rjs.2006.43762 | ||
| Authors | ||
| Subhi H. Al-Jobury; Isamail I. Al-Sanjari | ||
| Abstract | ||
| The study was conducted to isolate Moraxella catarrhalis form clinical specimens of Patients with Respiratory tract infection and to diagnose the strains by biochemical tests and API-NH system. Oroepithelial cells from human buccal cavity as in vitro adherence, mice trachea and lung as invivo adherence were used. The result showed that there was significant difference (p<0.0001) in adherence from one strain to another. The statistical analysis revealed that high levels adhesion rate of strains isolated from the sputum, throat, and nose in comparison to lower levels of strain from the ear with otitis media. It is found that the adherence has a correlation with the structural proteins on the outer surface of bacteria which may play a role in adherenceto be associated with occurrence of disease. Histopathological examination showed the high ability of M. catarrhalis to adhere and colonised to form bacteria aggregation on the epithelial cells of trachea and bronchoalveolar of mice. The influence adherence showed a negative result under physical and chemical factors :trypsin. Formalin (0.4%) temp. at 70C ْ and less than that at 60 C ْ compared with those non treatment. | ||
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