F.Al, N., Mejwel, , H.Al, F., Jawad, , A. Al-Ftahi, Y. (2006). Synthesis of 3„S - 3„S - gem ،- di ،- C ،VNitromethyl Nucleoside Analogues of Possible Biological Activity. , 15(1), 58-62.
Nidhal F.Al; Mejwel; Fuad H.Al; Jawad; Yousif A. Al-Ftahi. "Synthesis of 3„S - 3„S - gem ،- di ،- C ،VNitromethyl Nucleoside Analogues of Possible Biological Activity". , 15, 1, 2006, 58-62.
F.Al, N., Mejwel, , H.Al, F., Jawad, , A. Al-Ftahi, Y. (2006). 'Synthesis of 3„S - 3„S - gem ،- di ،- C ،VNitromethyl Nucleoside Analogues of Possible Biological Activity', , 15(1), pp. 58-62.
F.Al, N., Mejwel, , H.Al, F., Jawad, , A. Al-Ftahi, Y. Synthesis of 3„S - 3„S - gem ،- di ،- C ،VNitromethyl Nucleoside Analogues of Possible Biological Activity. , 2006; 15(1): 58-62.

Synthesis of 3„S - 3„S - gem ،- di ،- C ،VNitromethyl Nucleoside Analogues of Possible Biological Activity

Iraqi Journal of Pharmaceutical Sciences
Article 1, Volume 15, Issue 1, 2006, Pages 58-62
Authors
Nidhal F.Al; ; Fuad H.Al; ; Yousif A. Al-Ftahi
Abstract
Synthesis of new nucleoside analogues of the type : 3„S , 3„S - gem ،V di ،V C ،V nitromethly , expected to have useful application in the chemotherapeutic treatment of AIDS , cancer and microbial infections. The synthesis involved the condensation of the appropriate sugar derivative ( i.e . 3„S , 3„S ،V gem ،V di ،V C ،V nitromethly ،V 1،V ribofuranose ) with nitrogen bases , such as , uracil and theophllin following a multi step scheme starting from diacetone golucose (1) (scheme 1) .The prepared compound were identified by spectroscopic methods ; ir , mass , 1H and 13C nmr.
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