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Genotype Distribution of Angiotensin I- Converting Enzyme in Iraqi Arab Population | ||
| Iraqi Journal of Cancer and Medical Genetics | ||
| Article 1, Volume 4, Issue 2, 2011, Pages 24-29 | ||
| Authors | ||
| Ali Imad Mohmmad Moner; Wisam H. Salo; Abdulrahmahman A. Oleiwi; Abdulameer M. Ghareeb; Salwa J. Al-Awadi | ||
| Abstract | ||
| The angiotensin-converting enzyme (ACE) gene in humans has an insertion-deletion (I/D) polymorphic which produce three allelic variants: II, ID & DD that associated with population relativity and relation with many genetic disease. The polymorphisms of ACE gene were investigated using polymerase chain reaction. The results showed a high frequency of the DD allele among the Iraqi Arab populations (50%), which is similar to those obtained from previous studies for Arab populations. More ever the distribution of ACE genotype among male and female (n= 100, 53male & 47 female) showed DD: 47.17%, II: 22.6% & ID: 30.19% in the male group and DD: 40.43%, II: 17.02% & ID42.55:% in the female group. Significant association of hypertension & diabetic with D allele of the ACE gene has been in Iraqi Arab population. | ||
| Keywords | ||
| ACE; converting enzyme; ACE polymorphism | ||
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