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Differential Pulse Polarographic Assay of Azathioprine in Serum and Urine | ||
| Iraqi National Journal Of Chemistry | ||
| Article 1, Volume 0, Issue 39, 2014, Pages 616-623 | ||
| Author | ||
| Faris H. Abdul Razzak | ||
| Abstract | ||
| Abstract The polarographic behaviour of imuran (azathioprine) have been studied , the drug give a well sensitive defined double peaks at about (-0.4V, -0.96V) in carbonate buffer solution at pH 7.4 and at (-0.54V, -1.07 V) in serum – carbonate buffer and at (-0.42V, - 1.03 V) in urine – carbonate buffer. The lowest determined concentration was (8.7x10-7 M) in serum-carbonate media and (15.2x10-7 M) in urine-carbonate media. The method can be successfully applied to determination of azathioprine in vivo. The relation between concentration and diffusion current (Ip) was linear for all solutions. | ||
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