Antibiotic sensitivity patterns  of uropathogens isolated from females with urinary symptoms in Karbala

Ateyah Al-nasrawi, Adel; Mahmud Mousa Abu Almaali, Hassan

	Antibiotic sensitivity patterns of uropathogens isolated from females with urinary symptoms in Karbala
journal of kerbala university
Article 1, Volume 4, Issue 4, 2008, Pages 258-265 PDF (0 K)
Authors
Adel ateyah Al-nasrawi; Hassan mahmud mousa abu almaali
Abstract
Urinary tract infection is a common community-acquired bacterial disease which frequently affects female outpatients. Escherichia coli is the most common member of the family Enterobacteriaceae accounts for majority of all urinary tract infections in both inpatients and outpatients. Increasing rates of resistance among bacterial uropathogens has caused growing concern in both developed and developing countries, so that the objectives of this study are identifying the most frequent etiological agents of (U.T.I) in females and to determine their antibiotics sensitivity patterns.A total of (470) adult females were enrolled in this study. Middle stream urine samples were collected and cultured according to standard methods. The positive cultures(140)were tested for antibiotics sensitivity by using Kirby-Bauer's disk diffusion method.The predominant uropathogen was Escherichia coli 62 (44.4%), followed by Pseudomonas aeruginosa 28 (20%), Salmonella species 18 (12.8%), Klebsiella pneumonia 16(11.4 %), Shigella species 12 (8.6%), and Serratia species 4 (2.8%). We found that 76% of Escherichia coli isolates were sensitive to Ciprofloxacin, (41%)for Trimethoprim, 41% for Nalidixic acid, 8% for Carbencillin, 57% for Nitrofurantoin, 27% for Cefotaxime, 0% for Ampicillin, 3% for Oxacillin, 42% for Trimethoprim- sulfamethoxazole, 54% for Gentamicin . wile 59% of Pseudomonas aeruginosa isolates were sensitive to Ciprofloxacin, 30% for Trimethoprim, 46% for Nalidixic acid, 16% for Carbencillin, 47% for Nitrofurantoin, 15% for Cefotaxime, 8% for Ampicillin, 33% for Trimethoprim- sulfamethoxazole , 57% for Gentamicin all pseudomonas isolates were resistance for Oxacillin. In addition , 88% of Salmonella species were sensitive to Ciprofloxacin, 22% for Trimethoprim, 66%for Nalidixic acid, 11% for Nitrofurantoin , ,22% for Oxacillin , 44% for Trimethoprim- sulfamethoxazole , 88% for Gentamicin all salmonella isolates were resistant to Carbencillin , Cefotaxime and Ampicillin. Also, 100% of Klebsiella pneumonia were sensitive to Ciprofloxacin , 42% for Trimethoprim , 71% for Nalidixic acid , 20% for Carbencillin , 37% for Nitrofurantoin , 30% for Cefotaxime , 25% for Ampicillin , 13% for Oxacillin , 75% for Trimethoprim- sulfamethoxazole , 100% for Gentamicin .as well as 20 % of Shigella species were sensitive to Ciprofloxacin , as well as (20 %, 16 % , 23 % , 50% ) were sensitive for Trimethoprim- sulfamethoxazole , Nalidixic acid , Carbenicillin , Nitrofurantoin ,but thy were completely resistance for Cefotaxime , Ampicillin , Oxacillin, Gentamicin and Trimethoprim.and 100 % were sensitive for Nitrofurantoin .In addition 50 % of Serratia species isolates were sensitive to Ciprofloxacin ,Trimethoprim , Trimethoprim- sulfamethoxazole ,Gentamicin, Cefotaxime and Nalidixic acid , wile 100 % were resistant to Carbenicillin , Ampicillin , and Oxacillin .

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