AI-Ajely, M., A. Busheer, H., Abdul Ghnni, A. (2007). Synthesis and antibacterial evaluation of Some Pyrano-1,3-- Oxazine Derivatives. , 0(26), 348-356.
M.S. AI-Ajely; H. A. Busheer; A. Abdul Ghnni. "Synthesis and antibacterial evaluation of Some Pyrano-1,3-- Oxazine Derivatives". , 0, 26, 2007, 348-356.
AI-Ajely, M., A. Busheer, H., Abdul Ghnni, A. (2007). 'Synthesis and antibacterial evaluation of Some Pyrano-1,3-- Oxazine Derivatives', , 0(26), pp. 348-356.
AI-Ajely, M., A. Busheer, H., Abdul Ghnni, A. Synthesis and antibacterial evaluation of Some Pyrano-1,3-- Oxazine Derivatives. , 2007; 0(26): 348-356.

Synthesis and antibacterial evaluation of Some Pyrano-1,3-- Oxazine Derivatives

Iraqi National Journal Of Chemistry
Article 1, Volume 0, Issue 26, 2014, Pages 348-356
Authors
M.S. AI-Ajely; H. A. Busheer; A. Abdul Ghnni
Abstract
Abstract
Some dipeptide amide and amino derivatives of 7-chloro-4,5-dioxopyrano [3,4-e]-l,3-oxazine, compounds (2a-d) and (3a-e) respectively have been synthesized and studied against five species of bacteria in vitro. A significant activity against staph. Aureus and Bacelus Subtilis were observed by the above derivatives at concentration ranging from (0.1-10 mg./ml.) and remarkable activity was exhibited by 2-(N-glycyl glycine amido)-7-chloro-4,5-dioxopyrano [3,4-e]-l,3-oxazine (2a). Other compounds showed no significant activities. The I.R. and NMR spectral data of the synthesized compounds were also discussed and are included.
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