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Anti-inflammatory effect of Water and Alcoholic Extracts of Mushroom Agaricus bisporus in mice | ||
| journal of kerbala university | ||
| Article 1, Volume 5, Issue 2, 2009, Pages 30-35 PDF (0 K) | ||
| Abstract | ||
| The effect of water and alcoholic crude extracts of mushroom Agaricus bisporus against formalin-induced chronic inflammation in mice was studied after intra peritoneal (I.P) administration of three doses at concentrations of 333.3, 500 and 666.6 mg/kg for water extract and three doses at concentrations of 500, 1000 and 1500 mg/kg for alcoholic extract were achieved for 6 consecutive days. The results indicated that all doses of water and alcoholic crude extracts revealed significantly reduction in paw thickness at (P≤0.01) in 26, 62 and 63 % and 24, 37 and 55 % respectively, in comparison with 20% in mice with a standard drug (diclofenac 10 mg/kg). | ||
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