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Synthesis of substitutead 1,3-Oxazepine and 1,3-Diazepine Via Schiff Bases for Selfamethoxazole drug | ||
| karbala journal of pharmaceutical sciences | ||
| Article 6, Volume 1, Issue 1, 2010, Pages 49-58 PDF (0 K) | ||
| Author | ||
| Iman A. Yass | ||
| Abstract | ||
| Some of aldehydeamino-N-5-methyl-3-oxazolylbenzensulfonamide (Schiff bases) were prepared by condensation of Selfamethoxazole Drug with many substituted aldehydes. These Schiff bases were found to react with maleic anhydride,to give 1,3-Oxazepine-1,3-dione derivatives were react with primary aromatic amines to give the corresponding 1,3-Diazepine-4,7-dione. | ||
| Keywords | ||
| oxazepine; Diazepine; Selfamethoxazole drug | ||
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