Detection of the Demylination Changes in patients with Chronic Viral Hepatitis B by the Evaluation of the Nerve Conduction Study

Candidate,; H AbuRagheiff PhD, Mahdy

	Detection of the Demylination Changes in patients with Chronic Viral Hepatitis B by the Evaluation of the Nerve Conduction Study
KUFA MEDICAL JOURNAL
Article 1, Volume 15, Issue 1, 2012, Pages 110-121
Authors
; Mahdy H AbuRagheiff PhD
Abstract
Bachground: Segmental demyelination occurs when there is dysfunction or death of the Schwann cell or damage to the myelin sheath Segmental demyelination with slowed nerve conduction, of these, wallerian and axonal degeneration cause denervation and reduce the amplitude of compound action potential, whereas demyelination slows the nerve conduction with or without conduction block. Infection with HBV is one of the most common viral diseases affecting man; extrahepatic symptoms may result from deposition of antigen-antibody complexes formed when these particles are neutralized by anti-HBsAg antibodies. The pathogenesis of these extrahepatic disorders has not been fully elucidated but likely involves an aberrant immunologic response to extrahepatic viral proteins. The neurological manifestations of chronic hepatitis B viral are most often a peripheral sensory neuropathy characterized by numbness, burning and sensation of “pins and needles” peripheral motor neuropathy, mononeuropathy, mononeuropathy multiplex. Objectives: To assess the peripheral nerves abnormalities and detected the segmental demylination in chronic viral hepatitis B patients by using Nerve conduction study and to evaluate the relation between the sensory and motor peripheral neuropathy on different type of chronic viral hepatitis B
Keywords
chronic viral hepatitis B; sensory nerve conduction study; motor nerve conduction studies

Statistics Article View: 194 PDF Download: 152