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Evaluation of Serum Electrolytes and Uric Acid in Iraqi Epileptic Patients | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 9, Issue 1, 2010, Pages 84-87 PDF (0 K) | ||
| Author | ||
| Hind Hani Abdul Wahid | ||
| Abstract | ||
| ABSTRACT: BACKGROUND: Epileptic patients exhibited variably altered status of electrolytes, and antioxidant. OBJECTIVE: The aim of this study is to investigate the effect of epilepsy and long-term antiepileptic drug therapy on the level of serum electrolytes (calcium, sodium, and potassium) and antioxidant ( uric acid) . PATIENTS AND METHODS: Thirty epileptic patients and twenty normal healthy individuals as a control were recruited in this study. The mean± SD of age of treated and untreated patients was (24.0±10.0) and (31.0±11.0) respectively. Spectrophotometric technique was used to determine all the parameters in this study. Data were expressed as mean ± SD. Statistical comparison among different groups was performed by using ANOVA tests. Statistical significance was defined. as P<0.05. RESULTS: The treated group (particularly with valproate), show increases in the levels of calcium, sodium, with no difference in potassium. however among untreated epileptics, uric acid level was increased. CONCLUSION: The above parameters differs in epileptics comparable to controls and hence their correlation to seizures pathophysiology and their degree of control or resistance to antiepileptic drug therapy | ||
| Keywords | ||
| electrolyte; antiepileptic drug; Antioxidant | ||
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