STUDY OF ANTIMICROBIAL ACTIVITY OF SALVIA

	STUDY OF ANTIMICROBIAL ACTIVITY OF SALVIA
Iraqi Journal of Biotechnology
Article 1, Volume 7, Issue 1, 2008, Pages 51-63
Abstract
ABSTRACT Antimicrobial activity of cold aquous and ethanol extracts with four concentrations of each one (0.1, 0.2, 0.3 and 0.4 %) mg/ml of Salvia officinalis leaves were estimated against four types of pathogenic bacteria (E. coli, S. aureus, Klebsiella spp. and St. pyogenes) after incubation at (37)oC for (24)hr by usingWell Diffuion AssayMethod. Antimicrobial activity of both extracts was compared with that for a number of antibiotics include Ampicilin, Cephalexin, Erythromycin, Amoxicilin, Gentamicin and Tetracyclin by using antibiograme test. Both extracts of Salvia officinalis showed clear antimicrobial activity against pathogenic bacteria, which this activity was enhanced with the increasing of concentrations belongs to them. The latest concentration (0.4%)mg/ml of both extracts gave highest activity against E. coli, Klebsiella spp. and St. pyogenes with no antimicrobial activity against S. aureu and E. coli were the least testing bacteria affective by the concentrations of both extracts, while St. pyogenes was the most affective one. Antimicrobial activity of cold aquous and ethanol extracts of Salvia officinalis was better than that to Gentamicin against Klebsiella spp., while the antimicrobial activity of latest concentration of ethanolic extract against St. pyogenes was better than the effect of same antibiotic. The effect of Gentamicin , Erythromycin and Tetracyclin against E. coli was better than that of both extracts concentrations.The concentrations of both extracts had no clear antimicrobial activity against S. aureus ,which affect by Gentamicin and Tetracyclin. A resist of pathogenic bacteria to Ampicillin, Amoxicilin and Cephalexin was noticed.
Keywords
Antimicrobial activity; Salvia officinalis extracts; Pathogenic bacteria

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