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EFFECT OF VITEX AGNUS-CASTUS EXTRACT ON SOME PHYSIOLOGICAL PARAMETERS OF MICE (MUS MUSCULUS L.) | ||
| The Medical Journal of Basrah University | ||
| Article 1, Volume 25, Issue 2, 2007, Pages 57-59 PDF (0 K) | ||
| DOI: 10.33762/mjbu.2007.48269 | ||
| Author | ||
| Mustafa abd almajeed Hussein | ||
| Abstract | ||
| ABSTRACT Vitex (known locally as kaf murium) has along history of traditional use in women. The effect of alcoholic extract of vitex agnus-castus was examined for its effect on some blood parameters in mice (Mus Musculus). Mice in the treatment groups were injected intraperitoneally with two doses (6 mg and 12 mg / mouse) of vitex extract while the control group received distilled water daily for two weeks. Blood parameters (RBC, Hb, PCV) showed a significant decrease with both doses in comparison to the control group (P<0.01), while no significant decrease in (WBC) was found. Biochemical parameters (total serum protein, total serum cholesterol) showed a significant decrease in the treatment groups as compared with the control group (P<0.01). In conclusion, vitex agnus-castus alcoholic extract can have a significant adverse effect on blood. Its cholesterol lowering effect worths investigation in the future. | ||
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