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STUDY THE ANTIMICROBIAL ACTIVITY OF PROANTHOCYANIDIN (POCS) FROM GRAPE SEEDS | ||
| Iraqi Journal of Biotechnology | ||
| Article 1, Volume 10, Issue 2, 2011, Pages 217-226 | ||
| Abstract | ||
| ABSTRACT Proanthocyanidin (POCs) was extracted from grape seeds by liquid-liquid chromatography and identified via high performance liquid chromatography (HPLC).The antimicrobial activity of POCs was determined against nine of gram positive and gram negative bacterial strains and Candida albicans by agar well diffusion method and two strains of dermatophyte fungi Trichophyton interdigital and Trichophton menagraphytes. It was found that POCs has inhibition effect against Staphylococcus aureus, Streptococcus pyogenes and Bacillus subtilitis which gave inhibition zone (16, 14.5, 11) mm/ml respectively at the concentration 100mg /ml While there was low no inhibition effect against gram negative bacteria and Candida albicans, On the other hand the inhibition percentage against dermatophyte fungi T. interdigital and T.mentagraphytes increased with increasing the concentration of POCs which reached for 64.7%and 44.4%respectively | ||
| Keywords | ||
| Proanthocyanidin; Antimicrobial activity; grape seeds; Phenolic compound | ||
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