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Evaluation of serum FSH, LH and Testosterone levels in infertile patients affected with different male infertility factors after IUI technique | ||
| Thi-Qar Medical Journal | ||
| Article 1, Volume 4, Issue 3, 2010, Pages 112-122 | ||
| Authors | ||
| Amer Hassan Abed Khadim; Deyia Abed Oda Jazaa Al-Wayelli; Bassim Khamiss Kouti Al-Rekabe | ||
| Abstract | ||
| ABSTRACT : The present study was designed to evaluate the serum FSH, LH and testosterone levels in 75 infertile male affected with different male infertility factors. In this study, one hundred infertile males were involved and according to cause of infertility were divided into 25 normozoospermia, 25 oligozoospermia, and 25 asthenozoospermia infertile couples. From each male, semen samples were collected and sperm parameters including sperm concentration, sperm motility, progressive sperm motility, and normal sperm morphology were evaluated according to standard World Health Organization (WHO) criteria. For semen processing, sperm prepared using conventional layering technique through incubation for 30 minute in 5% CO2 at 37ºC.The results of the present study demonstrated that serum FSH and LH levels significantly (P<0.05) increase in infertile couples with normozoospermia, oligozoospermia, and decrease in asthenozoospermia as compare with fertile control group (No. =25). In contract, clearly significant decrease in serum testosterone levels (P<0.05) in infertile men with normozoospermia and oligozoospermia and non significant increase (P>0.05) in asthenozoospermia when compare with healthy fertile male. From the results of the present study, it was concluded that evaluation of serum FSH, LH, and Testosterone are diagnostic and prognostic tools in management of male infertility and acts as major control device of germ cell development. Further studies are recommended to assess the effect of elevated levels of FSH and LH and low levels of testosterone on DNA damage and embryo quality after in vitro fertilization and embryo transfer (IVF-ET). | ||
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