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Withdrawal effect of Chlorpromazine and Diazepam on chick blood (Plasma, Red Blood Cell) Acetyl cholinesterase activity | ||
| Journal of Education and Science | ||
| Article 5, Volume 19, Issue 1, 2007, Pages 36-40 PDF (0 K) | ||
| DOI: 10.33899/edusj.2007.51280 | ||
| Author | ||
| Luaay K. Yacoub | ||
| Abstract | ||
| Abstract Administration of chlorpromazine at ( 50 mg / kg / day ) orally for a period of 21 days resulted in a significant increase in chick blood plasma and RBC acetyl cholinesterase activity by 43 % and 63% respectively , where as only a slight and non significant increase was observed when diazepam was given at ( 30 mg / kg / day ) orally in comparison with control group . However once The drugs were been discontinued, the enzyme activity returned to pretreatment level in about 11-16 days in group received chlorpromazine, suggesting that the drugs effect is reversible. | ||
| Keywords | ||
| Chlorpromazine; Diazepam; drugs | ||
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