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Effect of a number of protein extractors and protein isolated from the fruit of tomato plant Solanaceae at the level of glucose, fat, clotathione and melonadialdehyde in mice with diabetes | ||
| Journal of Education and Science | ||
| Article 12, Volume 19, Issue 3, 2007, Pages 16-33 PDF (0 K) | ||
| DOI: 10.33899/edusj.2007.51311 | ||
| Authors | ||
| Shehab Al - Bajari; Mohammed Al-Sadoon; Omer Al-Abassi | ||
| Abstract | ||
| ABSTRACT This study was included prepare a cold aqueous extract of solanaceae fruit plant. The study also comprised the isolation and study the proteinaceous compounds, seperated by using the gel filtration technique which was isolated two compound A (52251) Dalton and B (6725) Dalton . The effects of these extracts and compounds previously mentioned above were studied on serum glucose , total cholesterol , triglyceride (TG) , low density lipoprotein-cholesterol ( LDL-C ) and high density lipoprotein-cholesterol ( HDL-C ) levels , also glutathione ( GSH ) and malondialdehyde ( MDA ) levels in liver, kidney and heart tissues in diabetic mice- induced alloxan. Extracts were administerated interaperitioneally. After one week from the treatment the results were indicated that the crude aqueous non proteinaceous extract , proteinaceous precipitate and proteinaceous compounds ( A ) and ( B ) which were caused a significat decrease in serum glucose, total cholesterol , TG, LDL-C leves and MDA level in liver , kidney and heart tissues , with an associated significant increase in serum HDL-C level and GSH level in liver , kidney and heart tissues , in alloxan-induced diabetic mice. finally we suggest that most of extracts isolated from fruit plant ( especially compound B ) have anti-diabetic effect in diabetic mice. | ||
| Keywords | ||
| Solanaceae; clotathione; melonadialdehyde | ||
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