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A Cloned Antigen (Recombinant K39) of Leishmania donovani Diagnostic for Visceral Leishmaniasis in Human | ||
| Journal Of Wassit For Science & Medicine | ||
| Article 1, Volume 3, Issue 1, 2010, Pages 12-18 | ||
| Authors | ||
| college of Science; Abdulsadah A.Rahi - Wasit University | ||
| Abstract | ||
| Visceral leishmaniasis (VL) or kala-azar is caused by an intracellular protozoan parasite of the Leishmania donovani complex and is considered as one of the most neglected diseases.To detect IgG antibody in the serodiagnosis of visceral leishmaniasis (VL), a recombinant antigen rK39, which is part of a Leishmania donovani kinesin-related protein, has been used successfully and showed high sensitivity and specificity. The rK39 dipstick showed a sensitivity of 95% (95 positive samples among 100 from VL patients) . The total human patients involved in this study were 100 divided into four age groups . Kala-azar infection found among children under one year old of the patient groups 60 (60 %).This higher rate than the other age groups which was began to decrease reaching to(1%) in age more than 40 years of age groups . Males were high infected 62 % (62/100) than females 38% (38/100)in patient groups Therefore, the ratio of male / female was 1.6 / 1. | ||
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