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Prolonged Bleeding Time in Uraemia | ||
| journal of kerbala university | ||
| Article 1, Volume 2, Issue 3, 2006, Pages 7-17 PDF (0 K) | ||
| Authors | ||
| Riyadh al- Saigh; Fuad Al- Kasab | ||
| Abstract | ||
| Bleeding is a common and sometime fatal event in uraemic patients. Its etiology is multifactorial.Eighty uremic patients were included in this study. 39 were males and 41 were females. Their ages ranged 18-70 years. They received haemodialysis (HD), peritoneal dialysis (PD) or both. Bleeding time (BT) was measured by intravenous method. BT is considered prolonged if it is > 10 minutes.This study found neither the patients' age nor their sex affect the BT. The effect of duration of the illness on BT is remarkable. HD affects BT while no effect for PD was found.The commonest clinical manifestation of uraemic bleeding tendency is epistaxis.Among the variable characters of uraemic patients that adversely affect BT were raised serum creatinine (S. cr.), low packed cell volume (PCV), and prolonged partial thromboplastin time (PTT).This study recommends measurement of BT as a simple bedside test for uraemic patients to identify the risk of bleeding at early time. Corrections of abnormal variables like:Anemia by eryhtropoiten and/or blood transfusion,azotemia by dialysis,3-DDAVP usage and/or cryoprecipitate for acute bleeding episode,and estrogen therapy and others.Have a good impact on treating bleeding in uraemics. | ||
| Keywords | ||
| Deamino; Arginine vasopressin; bleeding time; Haemodialysis; peritoneal dialysis; serum creatinine; packed cell volume; partial thromboplastin time; plate let; von Willebrand factor; Calcium ion; chronic renal failure; gastrointestinal tract; genitourinary tract; prothrombin time; white blood cell count; blood urea | ||
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