M. Salman MBCHB, A., Asst. Lecturer, M. (2010). Evaluation Of The Psychopharmacological Effects Of Loratadine With Concomitant Adminstration Of Erythromycin. , 13(1), 164-167.
Athra M. Salman MBCHB; MSC Asst. Lecturer. "Evaluation Of The Psychopharmacological Effects Of Loratadine With Concomitant Adminstration Of Erythromycin". , 13, 1, 2010, 164-167.
M. Salman MBCHB, A., Asst. Lecturer, M. (2010). 'Evaluation Of The Psychopharmacological Effects Of Loratadine With Concomitant Adminstration Of Erythromycin', , 13(1), pp. 164-167.
M. Salman MBCHB, A., Asst. Lecturer, M. Evaluation Of The Psychopharmacological Effects Of Loratadine With Concomitant Adminstration Of Erythromycin. , 2010; 13(1): 164-167.

Evaluation Of The Psychopharmacological Effects Of Loratadine With Concomitant Adminstration Of Erythromycin

KUFA MEDICAL JOURNAL
Article 1, Volume 13, Issue 1, 2010, Pages 164-167
Authors
Athra M. Salman MBCHB; MSC Asst. Lecturer
Abstract
Abstract
In this study, the effect of a single oral dose (10 mg) of a 2nd generation antihistaminic agent – loratadine - administered alone or with a metabolic inhibitor – erythromycin - on psychomotor performance was investigated on 6 healthy volunteers.
Recording of movement reaction time and assessment of subjective feeling of sedation was done before medication and hourly afterward for 3 hours.
The results were analyzed statically by using “student’s t test” which showed that loratadine erythromycin combination induced a statically significant impairment of psychomotor performance demonstrated by prolongation of finger tip reaction time.
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